Voltammetric estimation of the content of antibiotics inveterinary preparations

Abstract

The voltammetric method for determination of tylosin tartrate, gentamicin sulfate, and cefalexin in veterinary preparations was for the first time developed. Electrochemical behavior of these antibiotics on the mercury film electrode was studied, and the working conditions (background electrolyte, deposition potential) were defined for getting analytical signals using the voltammetry. The methods of real objects preparation for determination of tylosin tartrate, gentamicin sulfate, and cefalexin were offered. The techniques for the voltammetric determination of antibiotics in the veterinary preparations may be used in cefalexin ranging from 0.1 to 2.0 g/dm{³}, tylosin tartrate in the range from 0.1 to 1.7 g/dm{³}, and gentamicin sulfate from 0.1 to 1.5 g/dm{³} (Sr is not more than 25 %).