Получение биосовместимых магнитоэлектрических наночастиц со структурой «ядро-оболочка» микроволновым гидротермальным синтезом

Abstract

Nowadays, magnetoelectric (ME) micro-/nanoparticles have attracted a great interest among the scientists for biomedical applications due to their unique properties. In this present study, biocompatible ME core-shell nanoparticles (NPs) based on magnetostrictive MnFe2O4 (MFO) and ferroelectric Ba0,85Ca0,15Zr0,1Ti0,9O3 (BCZT) have been developed using microwave hydrothermal method (MHT). After 3 hours of MHT, on the MFO cores preliminarily treated with citric acid (CA) a successful formation of a thin epitaxial BCZT-shell was confirmed. Produced biocompatible ME NPs in the present study possess magnetic properties close to that of the most studied CoFe2O4 containing potentially toxic Co in spite of the reduced values of the saturation magnetization from 41,4±1,2 ± to 6,1±0,2 emu/g. Thus, it can be said that the developed biocompatible core-shell ME NPs of magnetostrictive MFO and ferroelectric BCZT can be considered as a promising tool for non-invasive biomedical applications (drug delivery, cancer treatment, etc.)