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Название: The use of {99m}Tc-Al[2]O[3] for detection of sentinel lymph nodes in cervical cancer patients
Авторы: Sinilkin, Ivan Gennadjevich
Chernov, Vladimir Ivanovich
Lyapunov, A. Yu.
Medvedeva, Anna Aleksndrovna
Zelchan, Roman Vladimirovich
Chernyshova, A. L.
Kolomiets, L. A.
Ключевые слова: лимфатические узлы; рак; радиофармпрепараты; компьютерная томография
Дата публикации: 2016
Издатель: IOP Publishing
Библиографическое описание: The use of {99m}Tc-Al[2]O[3] for detection of sentinel lymph nodes in cervical cancer patients / I. G. Sinilkin [et al.] // IOP Conference Series: Materials Science and Engineering. — 2016. — Vol. 135 : Issues of Physics and Technology in Science, Industry and Medicine : VIII International Scientific Conference, 1–3 June 2016, Tomsk, Russia : [proceedings]. — [012043, 5 p.].
Аннотация: The purpose of the study was to evaluate the feasibility of using {99m}Tc-Al[2]O[3]- based radiopharmaceutical, a novel molecular imaging agent for sentinel lymph node detection in patients with invasive cervical cancer. The study included 23 cervical cancer patients (TlaNxMx- T[2]bNxMx) treated at the Tomsk Cancer Research Institute. At 18 hours before surgery, 80 MBq of the {99m}Tc-Al[2]O[3] were injected peritumorally, followed by single-photon emission computed tomography (SPECT) of the pelvis and intraoperative SLN identification. Twenty-seven SLNs were detected by SPECT, and 34 SLNs were identified by intraoperative gamma probe. The total number of identified SLNs per patient ranged from 1 to 3(the mean number of SLNs was 1.4 per patient). The most common site for SLN detection was the external iliac region (57.2%), followed by the internal iliac, obturator, presacral and retrosacral regions (they amounted to 14%, respectively),and the parametrial region (1%). Sensitivity in detecting SLNs was 100% for intraoperative SLN identification and 79% for SPECT image.
URI: http://earchive.tpu.ru/handle/11683/34833
Располагается в коллекциях:Материалы конференций

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