Porosity and biocompatibility study of ceramic implants based on ZrO[2] and Al[2]O[3]

Abstract

The work studies ZrO[2](MexOy) -based porous ceramics produced from the powdersconsisting of hollow spherical particles. It was shown that the structure is represented by a cellular framework with bimodal porosity consisting of sphere-like large pores and pores that were not filled with the powder particles during the compaction. For such ceramics, the increase of pore volume is accompanied by the increased strain in an elastic area. It was also shown that the porous ZrO[2] ceramics had no acute or chronic cytotoxicity. At the same time, ceramicspossess the following osteoconductive properties: adhesion support, spreading, proliferation and osteogenic differentiation of MSCs.