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http://earchive.tpu.ru/handle/11683/46881
Название: | The Fabrication of Bioresorbable Implants for Bone Defects Replacement Using Computer Tomogram and 3D Printing |
Авторы: | Kuznetsov, P. G. Tverdokhlebov, Sergei Ivanovich Goreninsky, Semen Igorevich Bolbasov, Evgeny Nikolaevich Popkov, A. V. Kulbakin, D. E. Grigoryev, E. G. Cherdyntseva, N. V. Choynzonov, Evgeny Lkhamatsyrenovich |
Ключевые слова: | имплантанты; дефекты; кости; компьютерная томография; 3D-печать; полимеры; биоразлагаемые полимеры |
Дата публикации: | 2017 |
Издатель: | AIP Publishing |
Библиографическое описание: | The Fabrication of Bioresorbable Implants for Bone Defects Replacement Using Computer Tomogram and 3D Printing / P. G. Kuznetsov [et al.] // AIP Conference Proceedings. — 2017. — Vol. 1882 : Physics of Cancer: Interdisciplinary Problems and Clinical Applications (PC IPCA’17) : Proceedings of the International conference, 23–26 May 2017, Tomsk, Russia. — [020040, 1 p.]. |
Аннотация: | The present work demonstrates the possibility of production of personalized implants from bioresorbable polymers designed for replacement of bone defects. The stages of creating a personalized implant are described, which include the obtaining of 3D model from a computer tomogram, development of the model with respect to shape of bone fitment bore using Autodesk Meshmixer software, and 3D printing process from bioresorbable polymers. The results of bioresorbable polymer scaffolds implantation in pre-clinical tests on laboratory animals are shown. The biological properties of new bioresorbable polymers based on poly(lactic acid) were studied during their subcutaneous, intramuscular, bone and intraosseous implantation in laboratory animals. In all cases, there was a lack of a fibrous capsule formation around the bioresorbable polymer over time. Also, during the performed study, conclusions were made on osteogenesis intensity depending on the initial state of bone tissue. |
URI: | http://earchive.tpu.ru/handle/11683/46881 |
Располагается в коллекциях: | Материалы конференций |
Файлы этого ресурса:
Файл | Описание | Размер | Формат | |
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doi.org-10.1063-1.5001619.pdf | 1,65 MB | Adobe PDF | Просмотреть/Открыть |
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