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http://earchive.tpu.ru/handle/11683/35541| Title: | Voltammetric Sensor for Total Cholesterol Determination |
| Authors: | Derina, Kseniya Vladimirovna Korotkova, Elena Ivanovna Dorozhko, Elena Vladimirovna Voronova, Olesya Aleksandrovna Vishenkova, Dariya Aleksandrovna |
| Keywords: | холестерин; биосенсоры; холестерин; перекись водорода; вольтамперометрические датчики; вольтамперометрия; cholesterol; biosensor; horseradish peroxidase; cholesterol oxidase; hydrogen peroxide |
| Issue Date: | 2014 |
| Publisher: | Elsevier |
| Citation: | Voltammetric Sensor for Total Cholesterol Determination [Electronic resource] / K. V. Derina [et al.] // Procedia Chemistry . — 2014 . — Vol. 10 : Chemistry and Chemical Engineering in XXI century . — [P. 513-518] . |
| Abstract: | We report on a voltammetric sensor for the detection of total cholesterol. The sensor was fabricated by co-immobilization of two enzymes: cholesterol oxidase (ChOx) and horseradish peroxidase (HRP) on porous graphite. The electrochemical behavior of the sensor was studied with the use of linear sweep voltammetry. It has been shown that the sensor has high stability and high sensitivity (16 muA mM{-1} cm{-2}). The biosensor exhibited a wide linear range up to 300 mol/dm3 in a condition close to physiological (pH=6.86). Besides, the interferences of some key analytes containing in the blood were studied. As a matter of fact, making a fabricated sensor is rather promising for using in clinical practice. |
| URI: | http://earchive.tpu.ru/handle/11683/35541 |
| Appears in Collections: | Материалы конференций |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| dx.doi.org-10.1016-j.proche.2014.10.087.pdf | 331,91 kB | Adobe PDF | View/Open |
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